Our facility is provided with a quality assurance laboratory, equipped to analyse both raw materials and finished goods, a service we also provide to third parties. Microbiological studies, environmental quality and water quality controls are carried out as well.
Physicochemical testing laboratory
FID gas chromatography and Gas chromatography–mass spectrometry systems
Analysis:
Flame ionization detector gas chromatography or gas chromatography–mass spectrometry analysis
Use:
- Analysis of pesticides in animal and plant origin samples
- Analysis of residual solvents present in ethanol and hydroalcoholic extracts
- Analysis of impurities in glycerol
- Titration of active ingredients present in plant extracts
- Sterols and fatty acids analysis
- Raw materials titration
Ultra-performance liquid chromatography
Analysis:
High-performance liquid chromatography with mass detector or UV-Visible spectrophotometer analysis
Use:
- Analysis of pyrrolizidine alkaloids in plant extracts
High performance liquid chromatography with fluorometer
Analysis:
High-performance liquid chromatography with fluorescence detector
Use:
- Mycotoxin analysis
High performance liquid chromatography
Analysis:
High-performance liquid chromatography with UV-Visible detector analysis
Use:
- Analysis of preservatives such as Sodium Benzoate, Potassium Sorbate and Parabens
- Titration of active ingredients in plant extracts (Casticin, Cucurbitacin E, Verbenalin, Valerenic acid, Ferulic acid, Betulina, Hederacoside, Vanillin, Hyperoside, Quercitrin, Colchicine, Luteolin 7-glucoside, Strychnine/ Brucine, Hyoscine/ Hyoscyamine/ Nicotine, Convallatoxin, Berberine/ Hydrastine, Monoammonium Glycyrrhizinate, Harpagoside, Alfa-solanine, Silymarin, Alpha-Angelica lactone)
- Organic substances purity analysis
- Saccharin, Cholesterol, ATP, DHEA, Beta- Estradiol, Hydroquinone, Naphthoquinone, Anthraquinone, 1,4-Benzoquinone, Pentachlorophenol
Plasma optical and atomic emission spectrometer
Analysis:
Heavy metals analysis
Use:
- Analysis of plant and animal origin raw materials
- Titration and purity of materials
- Elements impurity analysis
- Immediate packaging material
Analysis:
- Refractive index analysis
- Brix degrees analysis
Use:
- Glycerol
- Glycerinated macerates
- Finished goods
- Sugar content
Thin Layer Chromatography
Analysis:
Qualitative and semiquantitative analysis of active ingredients, with UV lamp or visible detection
Use:
- Qualitative identification of plant samples
- Purity evaluation on samples and excipients (e.g. lactose, maltitol)
- Separation of the components of a mixture
Analysis:
- Redox titration
- Argentometric titration
- Iodometric titration/ iodimetry
- Acid-base titration
Use:
- Titration of active ingredients present in plant extracts
- Chemicals titration
Analysis:
Radioactivity analysis
Use:
- Analysis of radioactive content in raw materials
Analysis: optical rotation analysis
Use:
- Purity evaluation on raw materials and excipients (e.g. lactose)
Analysis:
Infrared absorption spectrometry on organic and inorganic compounds
Use:
Identification of raw materials and excipients (ethanol, glycerol, lactose, other chemicals)
Ultraviolet–visible spectrometer
Analysis:
Analysis of the absorption of single elements or classes of chemicals in the ultraviolet and visible region
Use:
Titration of active ingredients present in plant extracts (e.g. tannins, polyphenols, alkaloids, total flavonoids)
Analysis:
Acid base measurements
Use:
Analysis of raw materials purity (ethanol, glycerol, other chemicals)
In process pH inspection
Finished good pH inspection
Analysis:
Melting point analysis
Use:
Analysis of raw materials purity
Analysis:
Gastro-resistance evaluation
Use:
Measurement of the disintegration time of finished goods such as tablets and capsules in an acidic environment
Analysis:
Water titration
Use:
- Analysis of the water content in raw materials and excipients (e.g. lactose, glycerol, other chemicals)
- Analysis of the water content in glycerinated macerates of organs and venoms
Analysis:
Measurement of the viscosity of solutions
Use:
In process and finished good inspection (solutions and gels)
Analysis:
Evaluation of the endurance of sealing systems
Use:
Vials endurance analysis
Analysis:
conductivity measurement
Use:
water conductivity measurement
Analysis:
Analysis of ash and insoluble ash in animal samples
Analysis:
essential oils distillation
Analysis: Production of hydroalcoholic extracts from plants
Analysis: Accelerated stability testing
Analysis: Long-term stability testing
Analysis: preparation of freeze-dried products from extracts and other products
Analysis: Pharmacognostical identification of plant samples
Analysis on finished goods
Microbiological testing laboratory
Analysis: microbiological testing
Use:
Preparation of growth mediums for Petri dish, contact plates and for the Surface Air System (SAS) machine
Analysis: bacterial and fungal strains growth
Use:
- Growth medium fertility
- Bacterial titration
Analysis: growth of virus strains on cellules
Use:
Virus titration
Analysis: yeast and mould
Use:
Controls on raw materials, intermediate goods, immediate and outer packaging materials, finished goods, environmental analysis, sterility testing
Analysis: Escherichia coli
Use: Controls on raw materials, intermediate goods, immediate and outer packaging material, finished goods
Analysis: total bacterial count, Escherichia coli, Salmonella, Pseudomonas aeruginosa, Gram-negative bacteria, Staphylococcus aureus
Use:
Controls on raw materials, intermediate goods, immediate and outer packaging materials, finished goods, environmental analysis, sterility testing
Sterility testing laboratory
Analysis: environmental analysis
Use:
Air quality control in environmental cleanness A-B-C-D classes
Analysis: sterility testing
Use:
vials sterility inspection
Analysis: viral inactivation
Use:
Inactivation of raw materials of organic origin (nosodes, organs, animals, venoms, chemicals, immunologics)
Analysis: cell maintenance
Use:
ATCC cells maintenance
Analysis: extraction of DNA and RNA from cells to ensure the absence of DNA and RNA viruses
Use:
inspection of inactive materials and virus absence (ENTOROVIRUS, HEPATITIS A VRUS, HERPES SIMPLEX 1&2, HUMAN INFLUENZAE A&B, HUMAN PARAINFLUENZAE 1&3, 2&4, HUMAN PARVOVIRUA B19)
